35% OF EMPIRIC ATRIOVENTRICULAR DELAY SETTINGS MAY BENEFIT FROM ADDITIONAL OPTIMIZATION

AdipoRon may be benefit for atherosclerosis prevention

Atherosclerosis has serious role in coronary arteries disease,so it is important to establish effective strategies for prevention or even treatment of atherosclerosis. Adiponectin, as one of the most abundant adipokines, has insulin sensitivity, anti-inflammatory and anti-atherogenic properties. Disturbed adiponectin actions through its receptor, (AdipoR1 and AdipoR2) may be involved in atheros...

Evidence that conflict regarding size of haemodynamic response to interventricular delay optimization of cardiac resynchronization therapy may arise from differences in how atrioventricular delay is kept constant

AIMS Whether adjusting interventricular (VV) delay changes haemodynamic efficacy of cardiac resynchronization therapy (CRT) is controversial, with conflicting results. This study addresses whether the convention for keeping atrioventricular (AV) delay constant during VV optimization might explain these conflicts. METHOD AND RESULTS Twenty-two patients in sinus rhythm with existing CRT underwe...

Patients with uninjured lungs may also benefit from lung-protective ventilator settings

Although mechanical ventilation is a life-saving strategy in critically ill patients and an indispensable tool in patients under general anesthesia for surgery, it also acts as a double-edged sword. Indeed, ventilation is increasingly recognized as a potentially dangerous intrusion that has the potential to harm lungs, in a condition known as 'ventilator-induced lung injury' (VILI). So-called '...

Binswanger disease may benefit from omental arteries

Otto Binswanger lectured for the first time regarding the disease, eventually named after him, at the annual meeting of the German Lunatic‐Physicians in Dresden, Germany in 1894.[12] He claimed that he had followed eight cases for 11 years, and that there was “a strong atheromatosis of brain arteries,” which he explained lead to white matter atrophy as a result of chronic diffuse nutritional di...

Identifying patients who may benefit from treatment